学术简介：聚焦肿瘤、干细胞、表观遗传学和RNA生物学等方向，致力于鉴定肿瘤新标记物和治疗靶点，开展肿瘤和干细胞相关疾病的诊疗、靶向干预新策略研发等转化应用研究。以通讯作者/第一作者（共同）在Nature, Nature Metabolism, Molecular Cell (3篇), Nature Protocols, PNAS, Nature Communications (2篇), Gut，Cell Reports等杂志发表论文多篇。论文总被引超过1万次，多次入选“中国高被引学者”，“全球前2%顶尖科学家”，“全球高被引科学家”等榜单。主持国家杰出青年科学基金以及优秀青年科学基金，面上项目(2项)，国家重点研发计划国际科技创新合作重点专项，重点研发计划课题，广东省杰出青年基金，以及美国Damon Runyon Cancer Research Foundation等多项科研基金。担任美国基因和细胞治疗协会会刊Molecular Therapy 杂志 (Cell Press，IF=12.0) 副主编。

所获奖励
1. 2024  中山大学“芙兰奖”
2. 2020  中山大学附属第一医院柯麟奖
3. 2019  广东省“珠江人才计划”青年拔尖人才
4. 2018  广东省杰出青年医学人才
5. 2017  Young Investigator Award, Alex's Lemonade Stand Foundation. USA
6. 2013  Damon Runyon-Sohn Pediatric Cancer Fellowship Award, Damon Runyon Cancer Research Foundation. USA

五篇代表性论文（*共同第一，#共同通讯）
1.    Peng H*, Chen B*, Wei W*, Guo S*, Han H, Yang C, Ma J, Wang L, Peng S#, Kuang M#, Lin S#. N6-methyladenosine (m6A) in 18S rRNA promotes fatty acid metabolism and oncogenic transformation. Nature Metabolism. 2022 Aug;4(8):1041-1054.
2.    Ma J*, Zheng S*, An C*, Han H*, Li Q, Huang Y, Xiong G, Chen S, Guo S, Wang Z, Wei W, Shang Y, Ji Y, Yang C, Choe J, Yuan Q, Fan Y#, Zhang C#, Lin S#. Pathogenic mechanism and therapeutic intervention of impaired N7-methylguanosine (m7G) tRNA modification. Proceedings of the National Academy of Sciences. 2024 Nov 5;121(45):e2405886121. 
3.    Lin S#, Kuang M#. RNA modification-mediated mRNA translation regulation in liver cancer: mechanisms and clinical perspectives. Nature Reviews Gastroenterology & Hepatology. 2024 Apr;21(4):267-281. doi: 10.1038/s41575-023-00884-y. 
4.    Liu H*, Zeng X*, Ren X*, Zhang Y*, Huang M*, Tan L, Dai Z, Lai J, Xie W, Chen Z, Peng S, Xu L, Chen S, Shen S#, Kuang M#, Lin S#. Targeting tumor-intrinsic N7-methylguanosine tRNA modification inhibits MDSC recruitment and improves anti-PD-1 efficacy. Gut. 2023 Aug;72(8):1555-1567. 
5.    Han H*, Yang C*, Ma J*, Zhang S*, Zheng S*, Ling R, Sun K, Guo S, Huang B, Liang Y, Wang L, Chen S, Wang Z, Wei W, Huang Y, Peng H, Jiang YZ, Choe J, Lin S. N7-methylguanosine tRNA modification promotes esophageal squamous cell carcinoma tumorigenesis via the RPTOR/ULK1/autophagy axis. Nature Communications. 2022 Mar 18;13(1):1478.